A claim that the combination of Motrin and also Robitussin brand medications causes heart strikes in kids has not been developed by reliable medical evidence.

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Published11 February 2009

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We very first received an admonition no to combine Motrin through Robitussin via email in December 2008:

Medicine interaction!

Madison, period 8, pass away simply a few days ago. We’ve been asked to happen this on. Doctors told her family members that there have been fairly a few children Madison’s period that have passed away recently the same method that she did. The only common link in between them was that they were offered Motrin (ibuprofen) and also Robitussin together, this resulted in a love attack.

They believe this is what happened to them. Castle told her to alert anyone to this. Execute not give children both that these drugs together. Girlfriend can give them one or the other yet not both.

When Madison collapsed she suffered a love attack and also they to be able to revive her yet the lose of oxygen damaged her mind and she was put on the respirator.

After this she had 4 strokes before she passed away after gift taken off the respirator. Please pass this on.

The story the warning is framed upon, the an eight-year-old girl named Madison died from a heart attack and also strokes brought about by this mix of over-the-counter drugs, was unverifiable: the account noted no information as to Madison’s surname, wherein she lived, that her medical professionals were, wherein she was treated, or even the day she died. Lacking any of that information, do the efforts to determine if there actually was such a child verified a virtually impossible task.

It is possible that a child have the right to have a heart attack. Because that example, a news report of 2 October 2007 detailed heart assaults in children are a rare however under-recognized difficulty that are most likely brought about by heart spasms i m sorry briefly cut off the blood supply. It as such cannot it is in ruled out that a child dubbed Madison (of no known last name or address) did endure an acute myocardial infarction. However, the in rare instances youngsters have skilled heart attacks only proves that such events happen, not that any specific drug interaction reasons them.

The active ingredient in children Motrin is Ibuprofen, a nonsteroid anti-inflammatory drug efficient in relieving pain and also reducing inflammation. (Ibuprofen is likewise marketed under several other brand names, such as Advil, Medipren, and also Nuprin.) children’s Motrin Suspension first became obtainable as a prescription product in 1989, and also in 1995 it to be cleared through the Food and also Drug administration for marketing together an over-the-counter product. Both those landmarks developed only ~ the product had actually been extensively tested on children:


Before children’s Motrin became an over-the-counter product, its security profile was supported by a landmark examine involving nearly 84,000 children — among the largest and also most rigorous children clinical studies ever before conducted. The study spanned 3 years and included 1,735 physicians nationwide.

Robitussin Pediatric sneeze is a syrup that has Dextromethorphan HBr, a cough suppressant. That is Pediatric sneeze & Cold formulation consists of Chlorpheniramine maleate, an antihistamine, in addition to the Dextromethorphan HBr.

We have actually not however turned up any studies confirming heart attacks brought about by the mix of these two over-the-counter medications, one of two people in kids or adults, yet that is not to say children should be acquisition OTC cold medications. An 8 October 2008 declare by the FDA support the recommendation of the consumer Healthcare products Association that children under the age of four should not be dosed v over-the-counter cough and also cold products. This complies with its January 2008 advisory that these assets not be used in children under the period of 2 since of the risk of serious and potentially life-threatening side effects.

As listed in a news report indigenous September 2007: “An FDA evaluation of side-effect documents filed with the agency between 1969 and also September 2006 discovered 54 reports the deaths in children associated with decongestant medications made with pseudoephedrine, phenylephrine or ephedrine. It additionally found 69 reports the deaths associated with antihistamine medications containing diphenhydramine, brompheniramine or chlorpheniramine. Many of the deaths were kids younger than 2.”

The FDA supplies these medication advice to the parents and caregivers of small children:

Do no give youngsters medications labeled just for adults.Talk to your health treatment professional, such together your doctor or pharmacist, if you have any questions around using cough or cold medicines in children.Choose OTC cough and cold medicines with child-resistant security caps, when available. After each use, make sure to close the cap tightly and store the medications out that the sight and also reach of children.Check the “active ingredients” section of the “Drug Facts” brand of the medications that girlfriend choose. This ar will assist you understand what symptoms the energetic ingredients in the medicine are intended come treat. Cough and also cold medicines often have more than one energetic ingredient, such together an antihistamine, a decongestant, a sneeze suppressant, an expectorant, or a pains reliever and also fever reducer.Be very careful if you are giving much more than one medication to a child. Make certain the medicines do not have the same type of energetic ingredients. For example, perform not give a child more than one medicine that has actually a decongestant. If you use two medicines that have actually the exact same or similar active ingredients, her child could be harmed by getting too much of one ingredient.Carefully monitor the directions for just how to usage the medicine in the “Drug Facts” part of the label. This directions phone call you exactly how much medicine to give and also how often you can give it. If you have actually a question around how to usage the medicine, ask her pharmacist or various other health treatment professional. Overuse or misuse of these products can cause serious and potentially life-threatening side effects, together as quick heartbeat, drowsiness, breathing problems, and seizures.Only use measuring tools that come with the medicine or those specially created measuring drugs. Execute not use family spoons to measure medicines for children because household spoons come in various sizes and are not intended for measuring medicines.Understand that using OTC cough and cold drugs does no cure the cold or cough. These medications only treat her child’s symptoms, such as runny nose, congestion, fever, and also aches. They do not shorten the length of time your son is sick.

In 2003, another personal account circulated by e-mail implicated children’s Motrin in the development of stomach ulcers in a son dosed through it. We did not encounter any subsequent reports of comparable instances, and no certain interaction precaution indict exists because that that medicine combination.

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On 22 December 2014, children’s Medical facility of Dallas addressed the recirculating rumor top top Twitter:

If you’ve watched a facebook post about Motrin and also Robitussin, you re welcome read and share this. The information in the post is no correct and was not posted by one of our employees. Us encourage caregivers to discuss any over-the-counter medicines with your doctor and also to ask around information uncovered on the Internet.